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Primary spinal intradural extramedullary diffuse large b-cell lymphoma at the cervical-thoracic junction mimicking meningioma: A case report and literature review

  • Lina . ,
  • Sabri Ibrahim ,

Abstract

Background: Primary spinal intradural extramedullary lymphoma (PSIEL) remains a rare disease in spine oncology that is frequently misdiagnosed. In this report, we present the case of an intradural extramedullary lesion at the C6-T1 level that turned out to be a diffuse large B-cell lymphoma (DLBCL) as the seventh case of PSIEL in the literature.

Case presentation: We present a case of primary spinal intradural extramedullary DLBCL at the cervicothoracic junction (C6-T1) in a 41-year-old woman with the symptom of nuchal pain radiating to the right hand, followed by progressive tetraparesis. Pre-operative cervical magnetic resonance imaging (MRI) mimicked a meningioma. The patient was misdiagnosed with meningioma and underwent laminectomy tumor removal and laminoplasty. DLBCL was confirmed after surgery eventually by histopathology and immunochemistry examination. This was the seventh reported case of PSIEL. Characteristics of the tumor, pathogenesis, radiological findings, and management of spinal DLBCL were discussed and related literature was reviewed.

Conclusion: In cases when an intradural extramedullary lymphoma is suspected, a comprehensive systemic post-operative evaluation including histopathology is required.

Keywords: B-cell lymphoma, intradural extramedullary tumor, meningioma, primary spinal lymphoma

How to Cite

., L., & Ibrahim, S. (2024). Primary spinal intradural extramedullary diffuse large b-cell lymphoma at the cervical-thoracic junction mimicking meningioma: A case report and literature review. Indonesian Journal of Neurosurgery, 7(1), 11–15. https://doi.org/10.15562/ijn.v7i1.261

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